Antibody-Binding Proteins and Conjugates
Cayman Chemical RosIglItazonpotasIum salt 50mg
A PPARγ agonist; activates PPARγ1 and PPARγ2 in reporter assays (EC50s = 30 and 100 nM, respectively); selectively activates chimeras containing the LBDs of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 mM; an inhibitor of ACSL4 (IC50 = 0.5 µM), inhibits RSL3-induced ferroptosis in Pfa1 cells and Pparg KO cells, and increases survival in a Gpx4 KO mouse model of ferroptosis at 0.0125 mg/ml in the drinking water; decreases HbA1c and fasting blood glucose levels in a rat model of type 2 diabetes induced by STZ and a high-carbohydrate and high-fat diet at 4 mg/kg
Biotium CD106 / VCAM1(1.4C3), CF488A conjugate, 0.1mg/mL
CD106 (also known as vascular cell adhesion molecule-1, or VCAM-1) is a member of the Ig superfamily of adhesion molecules. It is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte beta-1 integrin VLA-4 and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Cayman Chemical FusIdIc AcIdodIum salt 50mg
A fusidane antibiotic; active against a variety of Gram-positive bacteria (MIC50s = 0.01-20 UG/ml) but not Gram-negative bacteria or fungi (MIC50s = >100 UG/ml for all); inhibits EF-G-mediated ribosomal recycling and protein translocation in isolated E. coli ribosomes (IC50s = ~0.1 and ~200 µM, respectively); reduces the number of skin CFUs and levels of TNF-α and IL-6 in a mouse model of MRSA skin wound infection
Cayman Chemical RhodamIn 101Inr salt 500mg
A bright fluorescent dye with excitation and emission maxima of 565 and 595 nm, respectively
Jackson Immuno Research Labs Cy5-ChromPure Goat IgG whole molecule
Cy5-ChromPure Goat IgG whole molecule
Jackson Immuno Research Labs Alexa Fluor 680-ChromPure Mouse IgG whole molecule
Alexa Fluor 680-ChromPure Mouse IgG whole molecule
Cayman Chemical XtsodIum salt hydrate 50mg
A cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator
Abcam PE / R-Phycoerythrin Conjugation Kit - Lightning-Link, 1 x 3MG
The Abcam PE/R-Phycoerythrin Conjugation Kit (ab102918) offers several standout features: -Rapid Conjugation: achieve PE/R-Phycoerythrin labeling in under 4 hours with just 30 seconds of hands-on time. -High Efficiency: ensures 100% antibody recovery, preserving the integrity and value of your antibodies. -Versatility: suitable for conjugating antibodies, proteins, and peptides, and the labeled antibodies can be used immediately in applications such as Western Blotting (WB), ELISA, and Immunohistochemistry (IHC) without further purification. - Confidence: cited in over 50 publications
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical MethIcIlInsodIum salt 50mg
A semisynthetic penicillin antibiotic that can inhibit bacterial cell wall synthesis; used to study methicillin-resistance in S. aureus
Cayman Chemical OlsalazInsodIum salt 500mg
A prodrug form of 5-ASA; increases ion transport in isolated rabbit distal ileum when applied to the luminal side (ED50 = 0.3 mM); stimulates fluid transport in rat jejunum (5 mM); improves stool consistency and decreases occult and gross bleeding as well as MPO activity and LTB4 levels in colon tissue in a mouse model of dextran sulfate-induced colitis (150 mg/kg for 8 days); inhibits bovine xanthine oxidase in vitro (IC50 = 3.4 mg/L); lowers serum uric acid levels in an oxonic acid-induced mouse model of hyperuricemia (20 mg/kg)